BCMA Gene Sequence, Family, Fuction and Expression Information
BCMA cDNA / Gene Overview
TNFRSF17 gene / cDNA is a protein-coding gene which located on 16p13.13. The TNFRSF17 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat.190 organisms have orthologs with human gene TNFRSF17.
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is preferentially expressed in mature B lymphocytes, and may be important for B cell development and autoimmune response. This receptor has been shown to specifically bind to the tumor necrosis factor (ligand) superfamily, member 13b (TNFSF13B/TALL-1/BAFF), and to lead to NF-kappaB and MAPK8/JNK activation. This receptor also binds to various TRAF family members, and thus may transduce signals for cell survival and proliferation. [provided by RefSeq, Jul 2008]
BCMA cDNA / Gene Sequence
LOCUS NM_001192 994 bp mRNA linear PRI 23-JUN-2018
Homo sapiens TNF receptor superfamily member 17 (TNFRSF17), mRNA.
This sequence information is just for reference only.
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