C9 Gene Sequence, Family, Fuction and Expression Information
C9 cDNA / Gene Overview
C9 cDNA / gene is a gene with protein product which located on 5p13.1. The C9 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and frog. 236 organisms have orthologs with human gene C9.
This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009]
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