C9 Gene Sequence, Family, Fuction and Expression Information

C9 cDNA / Gene Overview

C9 cDNA / gene is a gene with protein product which located on 5p13.1. The C9 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, and frog. 236 organisms have orthologs with human gene C9.

C9 cDNA / Gene Function

This gene encodes the final component of the complement system. It participates in the formation of the Membrane Attack Complex (MAC). The MAC assembles on bacterial membranes to form a pore, permitting disruption of bacterial membrane organization. Mutations in this gene cause component C9 deficiency. [provided by RefSeq, Feb 2009]

C9 Family & Reagents

Gene family

C9 Gene family reagents (Complement system)

Approved Symbol Reagent list
C1QB
C3
C6
CD46
CFB
CFH
CFHR2
Approved Symbol Reagent list
C2
C5
C7
CD59
CFD
CFHR1
CR2

C9 cDNA / Gene Expression

Restricted expression toward liver (RPKM 365.0)