CDC37 Gene Sequence, Family, Fuction and Expression Information
CDC37 cDNA / Gene Overview
CDC37 gene / cDNA is a protein-coding gene which located on 19p13.2. The CDC37 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, zebrafish, fruit fly, mosquito, C.elegans, and frog.213 organisms have orthologs with human gene CDC37.
The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008]
CDC37 cDNA / Gene Sequence
LOCUS NM_007065 1693 bp mRNA linear PRI 03-JUN-2018
Homo sapiens cell division cycle 37 (CDC37), mRNA.
This sequence information is just for reference only.
CDC37 cDNA / Gene Alias
CDC37 (cell division cycle 37
CDC37 cell division cycle 37 homolog
Hsp90 co-chaperone Cdc37
CDC37 cDNA / Gene Expression
Ubiquitous expression in fat (RPKM 70.6), spleen (RPKM 61.9) and 25 other tissues
Recombinant CDC37 protein citations
Competitive profiling of celastrol targets in human cervical cancer HeLa cells via quantitative chemical proteomics
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