CDC37 Gene Sequence, Family, Fuction and Expression Information

CDC37 cDNA / Gene Overview

CDC37 gene / cDNA is a protein-coding gene which located on 19p13.2. The CDC37 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, zebrafish, fruit fly, mosquito, C.elegans, and frog.213 organisms have orthologs with human gene CDC37.

CDC37 cDNA / Gene Function

The protein encoded by this gene is highly similar to Cdc 37, a cell division cycle control protein of Sacchromyces cerevisiae. This protein is a molecular chaperone with specific function in cell signal transduction. It has been shown to form complex with Hsp90 and a variety of protein kinases including CDK4, CDK6, SRC, RAF-1, MOK, as well as eIF2 alpha kinases. It is thought to play a critical role in directing Hsp90 to its target kinases. [provided by RefSeq, Jul 2008]

CDC37 cDNA / Gene Sequence

LOCUS
LOCUS NM_007065 1693 bp mRNA linear PRI 03-JUN-2018
DEFINITION
Homo sapiens cell division cycle 37 (CDC37), mRNA.
ACCESSION
NM_007065
VERSION
NM_007065.3

This sequence information is just for reference only.

CDC37 cDNA / Gene Alias

  • CDC37 (cell division cycle 37
  • S. cerevisiae
  • homolog)
  • CDC37 cell division cycle 37 homolog
  • Hsp90 co-chaperone Cdc37
  • P50CDC37

CDC37 cDNA / Gene Expression

Ubiquitous expression in fat (RPKM 70.6), spleen (RPKM 61.9) and 25 other tissues

Recombinant CDC37 protein citations

Title
Competitive profiling of celastrol targets in human cervical cancer HeLa cells via quantitative chemical proteomics
Year
2016
Author
Zhou, Y;Li, W;Wang, M;Zhang, X;Zhang, H;Tong, X;Xiao, Y;
Journal
Mol Biosyst