CRTAM Gene Sequence, Family, Fuction and Expression Information

CRTAM cDNA / Gene Overview

CRTAM gene / cDNA is a protein-coding gene which located on 11q24.1. The CRTAM gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and zebrafish.231 organisms have orthologs with human gene CRTAM.

CRTAM cDNA / Gene Function

The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A; MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains (Yeh et al., 2008 [PubMed 18329370]).[supplied by OMIM, Feb 2009]

CRTAM cDNA / Gene Sequence

LOCUS
LOCUS NM_019604 2471 bp mRNA linear PRI 07-AUG-2018
DEFINITION
Homo sapiens cytotoxic and regulatory T cell molecule (CRTAM), transcript variant 1, mRNA.
ACCESSION
NM_019604
VERSION
NM_019604.3

This sequence information is just for reference only.

CRTAM Family & Reagents

CRTAM Gene family reagents (CD molecules)

Approved Symbol Reagent list
ICAM1
IL2RG
TNFRSF10B
CD53
BTLA
PTPRC
CD83
IL2RA
ENG
PLAUR
Approved Symbol Reagent list
CD1D
TNFRSF13B
KLRK1
FCGR2A
SELPLG
TNFSF14
CEACAM6
CD70
ICOS
CD200

CRTAM Gene family reagents (V-set domain containing)

Approved Symbol Reagent list
CD7
CD300A
VSIG4
CD79B
SIGLEC6
NCR2
JAM3
BTN3A3
TREML2
CD28
Approved Symbol Reagent list
MPZL3
SCN3B
PILRA
SIGLEC15
SIGLEC5
ESAM
IGSF8
CD83
SLAMF7
CD86

CRTAM Gene family reagents (C2-set domain containing)

Approved Symbol Reagent list
NECTIN2
NECTIN4
SIGLEC10
TMEM25
NECTIN3
CADM2
KIRREL3
CD22
KIRREL2
NECTIN1
Approved Symbol Reagent list
CD4
CADM1
CD276
AGER
BTN3A1
CD80
KIRREL1
MCAM
CD200R1
MAG

CRTAM Gene family reagents (Ig-like cell adhesion molecule family)

Approved Symbol Reagent list
ICAM1
ICAM3
VCAM1
CADM3
CHL1
JAML
ICAM2
CADM2
CADM4
UNC5B
Approved Symbol Reagent list
CNTN1
NECTIN2
UNC5A
ICAM5
IZUMO1
ALCAM
MCAM
NFASC
CNTN2
NECTIN3

CRTAM cDNA / Gene Alias

  • CD355
  • class I MHC restricted T cell associated molecule

CRTAM cDNA / Gene Expression

Biased expression in lymph node (RPKM 4.2), spleen (RPKM 1.7) and 11 other tissues