DLL4 Information: DLL4 Protein, DLL4 Antibody and DLL4 Gene

DLL4 Protein

DLL4 protein function

Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344). {ECO:0000250|UniProtKB:Q9JI71, ECO:0000269|PubMed:11134954, ECO:0000269|PubMed:17728344, ECO:0000269|PubMed:20616313}.

DLL4 protein expression

Tissue specificity

Expressed in vascular endothelium.

DLL4 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (Da)

DLL4 Antibody

There are 9 DLL4 antibodies which are validated in multiple tissues with various applications, including ELISA, ELISA(Cap), ELISA(Det). There are 8 DLL4 antibody for ELISA, 2 DLL4 antibody for ELISA(Cap), 1 DLL4 antibody for ELISA(Det). Among all these DLL4 antibodies, there are 2 anti-DLL4 mouse monoclonal antibodies , 3 anti-DLL4 rabbit monoclonal antibodies , 4 anti-DLL4 rabbit polyclonal antibodies . All the DLL4 anbodies are produced in house and all are in stock. DLL4 antibody customerized service is available.

DLL4 Gene

DLL4 gene / cDNA is a protein-coding gene which located on 15q15.1. The DLL4 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, and frog.232 organisms have orthologs with human gene DLL4.