FZD1 Protein Overview: Sequence, Structure, Function and Protein Interaction

FZD1 Protein Overview

FZD1 reagents

Frizzled proteins, such as FZD1, are 7-transmembrane domain-containing receptors whose extracellular cysteine-rich domains (CRDs) bind to Wnt proteins (see 164975). Wnts are secreted cell signaling proteins involved in development and homeostasis (summary by Zilberberg et al., 2004).

FZD1 protein family

Belongs to the G-protein coupled receptor Fz/Smo family.

FZD1 protein name

Recommended name
Frizzled-1
Short name
Fz-1||hFz1
Aliases
DKFZp564G072, frizzled, Drosophila, homolog of, 1, Wnt receptor
Alternative name
FzE1

FZD1 Gene family protein

FZD1 Protein Sequence

Species Human FZD1 protein
Length 647
Mass (Da) 71158
Sequence Human FZD1 protein sequence
Species Mouse FZD1 protein
Length 642
Mass (Da) 71127
Sequence Mouse FZD1 protein sequence
Species Rat FZD1 protein
Length 641
Mass (Da) 71027
Sequence Rat FZD1 protein sequence

FZD1 Protein Molecular Weight & PI

Frizzled-1 precursor (Fz-1) (hFz1) (FzE1) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 70-647 Frizzled-1.

Molecular weight (Da)

63899.92

Theoretical pI

8.26

FZD1 Protein Interaction

Recombinant FZD1 Protein Feature

FZD1 Protein, Mouse, Recombinant (His Tag)

High Purity
> 97 % as determined by SDS-PAGE
Low Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method

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