IL-22BP cDNA Clone: Expression and Clone Vector / Plasmid

IL-22BP cDNA / Gene Overview

IL22RA2 gene / cDNA is a protein-coding gene which located on 6q23.3. The IL22RA2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, and zebrafish.191 organisms have orthologs with human gene IL22RA2.

IL-22BP cDNA / Gene Function

This gene encodes a member of the class II cytokine receptor family. The encoded soluble protein specifically binds to and inhibits interleukin 22 activity by blocking the interaction of interleukin 22 with its cell surface receptor. The encoded protein may be important in the regulation of inflammatory response, and has been implicated in the regulation of tumorigenesis in the colon. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]

IL-22BP cDNA / Gene Sequence

LOCUS
LOCUS NM_052962 2910 bp mRNA linear PRI 23-JUN-2018
DEFINITION
Homo sapiens interleukin 22 receptor subunit alpha 2 (IL22RA2), transcript variant 1, mRNA.
ACCESSION
NM_052962
VERSION
NM_052962.2

This sequence information is just for reference only.

IL-22BP Family & Reagents

Gene family

IL-22BP Gene family reagents (Interleukin receptors)

Approved Symbol Reagent list
IL1RN
IL1R1
IL20RA
IL5RA
IL3Ra
IL20RB
IL7R
IL31RA
IL1RAPL1
IL4R
Approved Symbol Reagent list
IL18RAP
IL12RB1
IL13Ra1
IL18R1
IL2RB
IL6R
IL1RAPL2
IL17RD
IL1RAP
IL1RL1

IL-22BP cDNA / Gene Alias

  • CRF2-S1
  • IL-22BP

IL-22BP cDNA / Gene Expression

Low expression observed in reference dataset