IL10RB Protein

IL10RB Protein Overview

IL10RB reagents

Class II cytokine receptor family (CRF2) members, such as IL10RB, are characterized by the presence of an extracellular domain composed of 2 subdomains of 100 amino acids.

IL10RB protein family

Belongs to the type II cytokine receptor family.

IL10RB protein name

Recommended name
Interleukin-10 receptor subunit beta
Short name
IL-10 receptor subunit beta||IL-10R subunit b
Aliases
CDW210B, CRF2-4, IL-10R2
Alternative name
Cytokine receptor class-II member 4 Cytokine receptor family 2 member 4 Interleukin-10 receptor subunit 2 CD_antigen: CDw210b

IL10RB Gene family protein

IL10RB Protein Sequence

Species Human IL10RB protein
Length 325
Mass (Da) 36995
Sequence Human IL10RB protein sequence
Species Mouse IL10RB protein
Length 349
Mass (Da) 39774
Sequence Mouse IL10RB protein sequence
Species
Length
Mass (Da)
Sequence

IL10RB Protein Molecular Weight & PI

Interleukin-10 receptor subunit beta precursor (IL-10 receptor subunit beta) (IL-10R subunit beta) (IL-10RB) (Cytokine receptor class-II member 4) (Cytokine receptor family 2 member 4) (CRF2-4) (Interleukin-10 receptor subunit 2) (IL-10R subunit 2) (IL-10R2) (CDw210b antigen) Homo sapiens (Human).

The parameters have been computed for the following feature

FT CHAIN 20-325 Interleukin-10 receptor subunit beta.

Molecular weight (Da)

35091.72

Theoretical pI

5.03

IL10RB Protein Structure

Structure of the IL-10R2 Common Chain
Deposited
2010-02-09   Released:  2010-05-26
Deposition Author(s)
Yoon, S.I., Walter, M.R.
Organism(s)
Homo sapiens
Experimental Data Snapshot
Method
X-RAY DIFFRACTION
Resolution
2.1400 Å
R-Value Free
0.239
R-Value Work
0.210
3LQM From PDB

Human IL10RB protein Secondary structure

IL10RB Protein Interaction

Recombinant IL10RB Protein Feature

IL10RB Protein, Human, Recombinant (His & Fc Tag)

High Purity
> 92 % as determined by SDS-PAGE
Low Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method
High Activity
Measured by its binding ability in a functional ELISA . Immobilized human IL28B at 20 μg/ml (100 μl/well) can bind human IL10RB-Fc with a linear ranger of 3.125-25 μg/ml.

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