IRTA1/FCRL4 Gene Sequence, Family, Fuction and Expression Information

IRTA1/FCRL4 cDNA / Gene Overview

FCRL4 cDNA / gene is a gene with protein product which located on 1q23.1. The FCRL4 gene is conserved in chimpanzee, Rhesus monkey, dog, and cow. 77 organisms have orthologs with human gene FCRL4.

IRTA1/FCRL4 cDNA / Gene Function

This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains three immune-receptor tyrosine-based inhibitory motifs. This protein may play a role in the function of memory B-cells in the epithelia. Aberrations in the chromosomal region encoding this gene are associated with non-Hodgkin lymphoma and multiple myeloma. [provided by RefSeq, Apr 2009]

IRTA1/FCRL4 cDNA / Gene Sequence

LOCUS
AF343661 3459 bp mRNA linear PRI 18-JUN-2001
DEFINITION
Homo sapiens immunoglobulin superfamily receptor translocation associated protein 1a (IRTA1) mRNA, complete cds, alternatively spliced.
ACCESSION
AF343661
VERSION
AF343661.1

This sequence information is just for reference only.

IRTA1/FCRL4 Family & Reagents

IRTA1/FCRL4 Gene family reagents (CD molecules)

Approved Symbol Reagent list
CLEC10A
CD207
LAIR1
L1CAM
CD274
CD34
IL21R
BMPR1A
FGFR2
CD14
Approved Symbol Reagent list
FCAR
CD2
PDCD1
IL18R1
IL13Ra2
TNFRSF12A
ENTPD1
NGFR
ICAM2
ICAM1

IRTA1/FCRL4 Gene family reagents (Immunoglobulin like domain containing)

Approved Symbol Reagent list
NPTN
CEACAM8
FCGR3B
CADM3
ICAM3
CD86
HepaCAM2
ICAM1
ICAM2
IL1RL2
Approved Symbol Reagent list
CLMP
CXADR
VSIG4
CD48
LAG3
IL1RAP
LY9
IL1RAPL1
PECAM1
CADM4

IRTA1/FCRL4 cDNA / Gene Alias

  • CD307d
  • FCRH4
  • IGFP2
  • IRTA1

IRTA1/FCRL4 cDNA / Gene Expression

Biased expression in lymph node (RPKM 2.4), appendix (RPKM 2.3) and 5 other tissues