MEK1 Gene Sequence, Family, Fuction and Expression Information

MEK1 cDNA / Gene Overview

MAP2K1 gene / cDNA is a protein-coding gene which located on 15q22.31. The MAP2K1 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.pombe, M.oryzae, N.crassa, A.thaliana, rice, and frog.230 organisms have orthologs with human gene MAP2K1.

MEK1 cDNA / Gene Function

The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008]

MEK1 cDNA / Gene Sequence

LOCUS
LOCUS NM_002755 2603 bp mRNA linear PRI 22-JUL-2018
DEFINITION
Homo sapiens mitogen-activated protein kinase kinase 1 (MAP2K1), mRNA.
ACCESSION
NM_002755
VERSION
NM_002755.3

This sequence information is just for reference only.

MEK1 Family & Reagents

MEK1 Gene family reagents (Mitogen-activated protein kinase kinases)

Approved Symbol Reagent list
MAP2K2
MAP2K6
Approved Symbol Reagent list
MAP2K4
   

MEK1 cDNA / Gene Alias

  • MAPKK1
  • MEK1

MEK1 cDNA / Gene Expression

Ubiquitous expression in brain (RPKM 34.3), fat (RPKM 20.3) and 25 other tissues