MS4A2 Information: MS4A2 Protein, MS4A2 Antibody and MS4A2 Gene

MS4A2 Gene family

MS4A2 Protein

MS4A2 protein function

High affinity receptor that binds to the Fc region of immunoglobulins epsilon. Aggregation of FCER1 by multivalent antigens is required for the full mast cell response, including the release of preformed mediators (such as histamine) by degranulation and de novo production of lipid mediators and cytokines. Also mediates the secretion of important lymphokines. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators responsible for the manifestations of allergy.

MS4A2 protein expression

Tissue specificity

Found on the surface of mast cells and basophils.

MS4A2 protein sequence

This sequence information is just for reference only.From Uniport

  • Length
  • Mass (KDa)

MS4A2 Gene

MS4A2 cDNA / gene is a gene with protein product which located on 11q12.1. The MS4A2 gene is conserved in chimpanzee, Rhesus monkey, dog, cow, mouse, and rat. 105 organisms have orthologs with human gene MS4A2.