Tubulin cofactor A (Protein | Antibody | cDNA Clone | ELISA Kit)

All Tubulin cofactor A reagents are produced in house and quality controlled, including 2 Tubulin cofactor A Antibody, 30 Tubulin cofactor A Gene, 1 Tubulin cofactor A Protein, 1 Tubulin cofactor A qPCR. All Tubulin cofactor A reagents are ready to use.

Tubulin cofactor A Protein (1)

    Tubulin cofactor A Antibody (2)

      Tubulin cofactor A cDNA Clone (30)

      Tubulin cofactor A qPCR Primer (1)

      Tubulin cofactor A Related Research Area

      Tubulin cofactor A Background

      Tubulin folding cofactor A belongs to the TBCA family. It is one of four proteins (cofactors A, D, E, and C) involved in the early step of the tubulin folding pathway. These proteins can fold intermediates and finally lead to correctly folded beta-tubulin. It is believed that tubulin folding cofactors A and D play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Tubulin folding cofactor E binds to the cofactor D/beta-tubulin complex; interaction with tubulin folding cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.

      Tubulin cofactor A References

      • Strausberg RL, et al. (2002) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci. 99(26):16899-903.
      • Irwin DM, et al. (2003) Molecular evolution of vertebrate goose-type lysozyme genes. J Mol Evol. 56(2):234-42.
      • Sklar P, et al. (2011) Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet. 43(10):977-83.